• LLLI caused potent dilation in the laser-irradiated arteriole, which led to marked increases in the arteriolar blood flow.
  • As a consequence of these changes, the blood flow (Q) showed a rapid initial increase even at ~1 minute after LLLI (increase in the early phase), and continued to increase till 30 minutes after LLLI (increase in the delayed phase), finally leveling off at ~200% of the preirradiation value
  • In conclusion, we have shown that laser irradiation at a wavelength of 830 nm is a potent dilator of the arteriole and consequently causes a marked increase in blood flow in the rat microvascular bed. Nitric oxide seems partly involved in the vasodilation that occurs in the early phase.


Low-intensity laser irradiation improves skin circulation in patients with diabetic microangiopathy